Anthranilate Synthetase from Serratia marcescens

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Anthranilate synthetase. Some physical and kinetic properties of the enzyme from Serratia marcescens.

Anthranilate synthetase from Serratia marcescens was purified to homogeneity. Criteria for homogeneity were disc gel electrophoresis, sedimentation analysis, and immunodiffusion. During electrofocusing the enzyme was found to have an isoelectric pH of 4.6. Glutamineand ammoniadependent activities superimposed during electrofocusing. Glutamine-dependent activity showed a pH optimum of 7.6, while...

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In recent years, Serratia marcescens has become established in certain localities as an agent of hospital infection and cross-infection (Clayton & von Graevenitz, 1966; Wilfert, Barrett & Kass, 1968; Davis, Foltz & Blakemore, 1970; Wilkowske, Washington, Martin & Ritts, 1970). In general, strains of S. marcescens isolated from infective lesions differ from those from other sources in being non-...

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ژورنال

عنوان ژورنال: Journal of Biological Chemistry

سال: 1972

ISSN: 0021-9258

DOI: 10.1016/s0021-9258(19)44856-4